| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 7754198 | Journal of Inorganic Biochemistry | 2018 | 10 Pages |
Abstract
Unconventional chiral diamine platinum(II) complexes with phenanthroline-based ligands induce lower cell death than cisplatin and distinct morphological changes in a non-cancerous renal cell line. Unlike cisplatin, this mode of action does not include oxidative stress, G2/M cell cycle arrest or genotoxicity commonly associated with DNA binding drugs.112
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Physical Sciences and Engineering
Chemistry
Inorganic Chemistry
Authors
Neville S. Ng, Ming J. Wu, Simon J. Myers, Janice R. Aldrich-Wright,