| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 7754244 | Journal of Inorganic Biochemistry | 2018 | 31 Pages |
Abstract
Substrate binding forms a narrow solvent-accessible tunnel, allowing O2 to react with the enzyme factor inhibiting HIF (FIH) while filtering out potential inhibitory compounds such as α-ketoglutarate.172
Related Topics
Physical Sciences and Engineering
Chemistry
Inorganic Chemistry
Authors
Vanessa D. Chaplin, Meaghan A. Valliere, John A. Hangasky, Michael J. Knapp,