| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 7754268 | Journal of Inorganic Biochemistry | 2018 | 58 Pages |
Abstract
Dual-acting Pt(II) complexes, designed to both inhibit selenocysteine glutathione peroxidase and bind to DNA, were shown to be cytotoxic to cancer cells, induced apoptosis, bind to nuclear DNA and interact with DNA in various ways. However, they do not inhibition glutathione peroxidase.200
Keywords
Related Topics
Physical Sciences and Engineering
Chemistry
Inorganic Chemistry
Authors
Heidi Lemmerhirt, Steven Behnisch, Anja Bodtke, Christopher H. Lillig, Lucia Pazderova, Jana Kasparkova, Viktor Brabec, Patrick J. Bednarski,