Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
7754449 | Journal of Inorganic Biochemistry | 2016 | 34 Pages |
Abstract
Results suggest that complexes 1 and 2 can bind to DNA via an intercalative mode and efficiently photocleavage pBR322 DNA in vitro under irradiation. In addition, the results of topoisomerase inhibition and DNA strand passage assay reflect that both complexes are efficient dual dual poisons of topoisomerases I and IIα.152
Related Topics
Physical Sciences and Engineering
Chemistry
Inorganic Chemistry
Authors
Yanmei Sun, Jia Li, Hong Zhao, Lifeng Tan,