| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 7754653 | Journal of Inorganic Biochemistry | 2016 | 35 Pages |
Abstract
Neurokinin B (NKB) outcompetes the prion protein (PrPC) for copper and undergoes rapid endocytosis, likely mediated by the G protein-coupled neurokinin 3 receptor receptor. This process suggests a mechanism for copper uptake that avoids cytosolic exposure and highlights how NKB could be involved in synaptic copper homeostasis.172
Related Topics
Physical Sciences and Engineering
Chemistry
Inorganic Chemistry
Authors
Reeha Shahzad, Mark R. Jones, John H. Viles, Christopher E. Jones,