New antibacterial, non-genotoxic materials, derived from the functionalization of the anti-thyroid drug methimazole with silver ions

Mixed ligand silver(I) complexes of the antithyroid drug methimazole (MMI): {[AgBr(μ2-S-MMI)(TPP))]2} (1) and [AgCl(TPP)2(MMI)] (2) (TPP = triphenylphosphine, were evaluated for their antibacterial effect against the bacterial species Pseudomonas aeruginosa (PAO) and Escherichia coli (E. coli). The in vivo genotoxicity of 1-2 was evaluated by Allium cepa test.117