Article ID Journal Published Year Pages File Type
7754748 Journal of Inorganic Biochemistry 2016 28 Pages PDF
Abstract
This work reports the preparation and characterization of five water-soluble Ru(II)- and Ru(III)-halide-PTA (PTA = 1,3,5-triaza-7-phosphaadamantane) complexes. The structure and pH dependent solution behavior of the compounds, their interactions with model proteins and with a single strand reference oligonucleotide, and their antiproliferative properties are discussed in comparison with established ruthenium drug candidates in clinical development.183
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Physical Sciences and Engineering Chemistry Inorganic Chemistry
Preview
Water-soluble Ru(II)- and Ru(III)-halide-PTA complexes (PTA = 1,3,5-triaza-7-phosphaadamantane): Chemical and biological properties
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