| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 7754933 | Journal of Inorganic Biochemistry | 2015 | 8 Pages |
Abstract
Synthesis and structural characterization of novel binuclear ruthenium compounds [Ru2O(carb)2(py)6](PF6)2, (py = pyridine; carb = ibuprofen 1 and ketoprofen 2) are reported. Compound 1 is metabolized by the cytochrome P450 enzymes, while compound 2 inhibits mast cell activation, suggesting its promising application as a therapeutic agent for treating or preventing IgE-mediated allergic diseases.157
Related Topics
Physical Sciences and Engineering
Chemistry
Inorganic Chemistry
Authors
Gabriela Campos Seuanes, Mariete Barbosa Moreira, Tânia Petta, Maria Perpétua Freire de Moraes Del Lama, Luiz Alberto Beraldo de Moraes, Anderson Rodrigo Moraes de Oliveira, Rose Mary Zumstein Georgetto Naal, Sofia Nikolaou,