| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 7754973 | Journal of Inorganic Biochemistry | 2015 | 9 Pages |
Abstract
We investigated the ability of aluminum compounds to trigger inflammatory and proteolytic pathways in U-937 human monocytic cell line. The cell treatment with Imject Alum induced increased levels of several cytokines and proteinases, suggesting these monocyte mediators as possible biomarkers for aluminum-linked diseases.
Keywords
MMPIP-10LPSPDGFGM-CSFMIPbFGFIL-1RAIFN-γBCAMCP-1Interleukin 1 receptor antagonistMultiplex immunoassayinterleukinbicinchoninic acidregulated on activation, normal T cell expressed and secretedCytokinesGranulocyte colony stimulating factorGranulocyte macrophage colony stimulating factorVascular endothelial growth factorVascular Endothelial Growth Factor (VEGF)platelet derived growth factorbasic fibroblast growth factorG-CSFTNF-αlipopolysaccharidematrix metalloproteinaseMatrix metalloproteinasesRANTESmonocyte chemotactic protein 1macrophage inflammatory proteininterferon gamma-induced protein 10ChemokinesAluminum chlorideInterferon gamma
Related Topics
Physical Sciences and Engineering
Chemistry
Inorganic Chemistry
Authors
D. Ligi, M. Santi, L. Croce, F. Mannello,