Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
7754974 | Journal of Inorganic Biochemistry | 2015 | 8 Pages |
Abstract
Trans diiodido platinum(II) complexes bearing the same as well as different aliphatic amines (mixed-amines) are examined in detail: cytotoxicity and interactions with some important biological models. Interestingly, UV irradiation of these compounds results in an increase in reactivity towards DNA in such model systems. Additionally, the cytotoxicity is noticeably increased by UV-light over short treatment times.146
Keywords
Related Topics
Physical Sciences and Engineering
Chemistry
Inorganic Chemistry
Authors
Francisco Navas, Stefanie Perfahl, Claudio Garino, Luca Salassa, Olga Novakova, Carmen Navarro-Ranninger, Patrick J. Bednarski, Jaroslav Malina, Adoración.G. Quiroga,