Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
7755033 | Journal of Inorganic Biochemistry | 2015 | 13 Pages |
Abstract
Three novel pyrimidinylhydrazones were synthesized and investigated for their anticancer potential. The most active derivative showed toxicity in the submicromolar range and was further investigated regarding the role of Fe(III) and Cu(II) complexation and reactive oxygen species in its mechanism of action.
Keywords
Related Topics
Physical Sciences and Engineering
Chemistry
Inorganic Chemistry
Authors
Veronika F.S. Pape, Dóra Türk, Pál Szabó, Michael Wiese, Eva A. Enyedy, Gergely Szakács,