| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 7755070 | Journal of Inorganic Biochemistry | 2014 | 31 Pages |
Abstract
The first lanthanide complexes with the anionic form of the bioactive ligand 5-methyl-1,2,4-triazolo[1,5-a]pyrimidin-7(4H)-one are described, in which sensitisation of lanthanide emission was observed. In vitro studies show their potential to become a new generation of highly effective and non-toxic antiparasitic agents to fight the neglected Chagas disease and leishmaniasis.137
Related Topics
Physical Sciences and Engineering
Chemistry
Inorganic Chemistry
![Lanthanide complexes containing 5-methyl-1,2,4-triazolo[1,5-a] pyrimidin-7(4H)-one and their therapeutic potential to fight leishmaniasis and Chagas disease](/preview/png/7755070.png "First Page Preview: Lanthanide complexes containing 5-methyl-1,2,4-triazolo[1,5-a] pyrimidin-7(4H)-one and their therapeutic potential to fight leishmaniasis and Chagas disease")
Authors
Ana B. Caballero, Antonio RodrÃguez-Diéguez, Juan M. Salas, Manuel Sánchez-Moreno, Clotilde MarÃn, Inmaculada RamÃrez-MacÃas, Noelia SantamarÃa-DÃaz, Ramón Gutiérrez-Sánchez,