Article ID Journal Published Year Pages File Type
7755437 Journal of Inorganic Biochemistry 2012 5 Pages PDF
Abstract
The Ru,Rh bimetallic complexes, [(bpy)2Ru(dpp)RhCl2(phen)]3 + and [(bpy)2Ru(bpm)RhCl2(phen)]3 + couple only one ruthenium polyazine light absorber to a cis-RhIIICl2 center and display visible light induced DNA binding and photocleavage via an oxygen independent mechanism. This previously unexplored structural motif for DNA modification holds promises in photodynamic therapy and DNA modification schemes.
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Physical Sciences and Engineering Chemistry Inorganic Chemistry
Preview
A new, bioactive structural motif: Visible light induced DNA photobinding and oxygen independent photocleavage by RuII, RhIII bimetallics
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