| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 7755462 | Journal of Inorganic Biochemistry | 2012 | 8 Pages |
Abstract
⺠Ru and Os arene complexes with Paullone ligands strongly inhibit cancer cell growth. ⺠Cytotoxicity correlates with inhibition of DNA synthesis and induction of apoptosis. ⺠Cdk2/cyclin E inhibition and cell cycle effects insufficiently explain cytotoxicity.
Related Topics
Physical Sciences and Engineering
Chemistry
Inorganic Chemistry
Authors
Gerhard Mühlgassner, Caroline Bartel, Wolfgang F. Schmid, Michael A. Jakupec, Vladimir B. Arion, Bernhard K. Keppler,