Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
7755471 | Journal of Inorganic Biochemistry | 2012 | 9 Pages |
Abstract
⺠Two copper thiosemicarbazonates cytotoxic effects are compared using U937 cells. ⺠The morpholine derivative is more effective in cell growth inhibition. ⺠The morpholine complex induces apoptosis. ⺠ROS and TBARS increased, GSH levels decrease and SOD is activated. ⺠The complexes differently interact with DNA and induce structure modifications.
Related Topics
Physical Sciences and Engineering
Chemistry
Inorganic Chemistry
Authors
Franco Bisceglie, Silvana Pinelli, Rossella Alinovi, Pieralberto Tarasconi, Annamaria Buschini, Francesca Mussi, Antonio Mutti, Giorgio Pelosi,