Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
7755479 | Journal of Inorganic Biochemistry | 2012 | 11 Pages |
Abstract
⺠Synthesis of the first water-soluble iminophosphorane(IM) ligand. ⺠Preparation of Pt(II) and Pd(II) compounds stable in physiological media. ⺠Pt and Au compounds cytotoxic to cisplatin resistant leukemia cell lines. ⺠Pt(II) shows an interaction with DNA weaker and different than that of cisplatin. ⺠All complexes interact with HSA faster than cisplatin (Pt in a reversible way).
Related Topics
Physical Sciences and Engineering
Chemistry
Inorganic Chemistry
Authors
Monica Carreira, Rubén Calvo-Sanjuán, Mercedes Sanaú, Xiangbo Zhao, Richard S. Magliozzo, Isabel Marzo, MarÃa Contel,