| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 7755576 | Journal of Inorganic Biochemistry | 2012 | 8 Pages |
Abstract
âºSynergism occurs between bortezomib and a novel histone deacetylase inhibitor. âºSynergism was associated with increased apoptotic cell death. âºp53-transcriptional transactivation inhibition enhanced the synergism âºKnockdown of wild-type p53 in IGROV-1 cells reduced synergism. âºThe transactivation-deficient mutant p53 is a determinant of the synergism.
Related Topics
Physical Sciences and Engineering
Chemistry
Inorganic Chemistry
Authors
Laura Gatti, Valentina Benedetti, Michelandrea De Cesare, Elisabetta Corna, Raffaella Cincinelli, Nadia Zaffaroni, Franco Zunino, Paola Perego,