Design, synthesis, anti-inflammatory antitumor activities, molecular modeling and molecular dynamics simulations of potential naprosyn® analogs as COX-1 and/or COX-2 inhibitors

Article ID	Journal	Published Year	Pages	File Type
7771649	Bioorganic Chemistry	2018	34 Pages	PDF

Keywords

COX-2 COX-1 Synthesis Antitumor screening Anti-inflammatory activity Docking studies

Related Topics

Physical Sciences and Engineering Chemistry Organic Chemistry

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Design, synthesis, anti-inflammatory antitumor activities, molecular modeling and molecular dynamics simulations of potential naprosyn® analogs as COX-1 and/or COX-2 inhibitors

Authors

Mardia T. El Sayed, Marwa A.M.Sh. El-Sharief, Eman S. Zarie, Nesrin M. Morsy, Ahmed R. Elsheakh, Mohammed Nayel, Andrey Voronkov, Vladimir Berishvili, Nermien M. Sabry, Ghada S. Hassan, Hatem A. Abdel-Aziz,