Probing the Î²-pocket of the active site of human liver glycogen phosphorylase with 3-(C-Î²-d-glucopyranosyl)-5-(4-substituted-phenyl)-1, 2, 4-triazole inhibitors

Article ID	Journal	Published Year	Pages	File Type
7771791	Bioorganic Chemistry	2018	9 Pages	PDF

Keywords

Inhibitor X-ray crystallography Glycogen metabolism Diabetes type 2 Glycogen phosphorylase

Related Topics

Physical Sciences and Engineering Chemistry Organic Chemistry

Preview

Probing the Î²-pocket of the active site of human liver glycogen phosphorylase with 3-(C-Î²-d-glucopyranosyl)-5-(4-substituted-phenyl)-1, 2, 4-triazole inhibitors

Authors

Efthimios Kyriakis, Theodora G.A. Solovou, Sándor Kun, Katalin Czifrák, Béla SzÅcs, László Juhász, Ãva Bokor, George A. Stravodimos, Anastassia L. Kantsadi, Demetra S.M. Chatzileontiadou, Vassiliki T. Skamnaki, László Somsák,