Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
7772105 | Bioorganic Chemistry | 2014 | 12 Pages |
Abstract
- PBP1B crystal structure access inhibition of its GTase activity.
- Inhibition of FtsZ polymerization cures mice from Staphylococcusaureus infection.
- FtsW and MraY activity assays and structures enable development of inhibitors.
- FtsQLB surface interaction studies enable search for inhibitors of this interaction.
- In cell screening assays based on specific targets are needed.
Keywords
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Tanneke den Blaauwen, José M. Andreu, Octavio Monasterio,