Article ID Journal Published Year Pages File Type
7772105 Bioorganic Chemistry 2014 12 Pages PDF
Abstract

- PBP1B crystal structure access inhibition of its GTase activity.
- Inhibition of FtsZ polymerization cures mice from Staphylococcusaureus infection.
- FtsW and MraY activity assays and structures enable development of inhibitors.
- FtsQLB surface interaction studies enable search for inhibitors of this interaction.
- In cell screening assays based on specific targets are needed.
Related Topics
Physical Sciences and Engineering Chemistry Organic Chemistry
Authors
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