Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
7772144 | Bioorganic Chemistry | 2012 | 5 Pages |
Abstract
⺠α-Lipoic acid derived N-phenylamides, 4a-e, were synthesized. ⺠4a-e were evaluated for their anti-proliferative effect on the LNCaP prostate cancer cell line. ⺠4a, b, d and e showed significant reductions in cell growth at concentrations of 5-20 μM. ⺠Compounds validated as an excellent platform for prostate cancer nanomedical applications.
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Authors
Luke C. Henderson, Jarrad M. Altimari, Gail Dyson, Linden Servinis, Birunthi Niranjan, Gail P. Risbridger,