Article ID Journal Published Year Pages File Type
7772144 Bioorganic Chemistry 2012 5 Pages PDF
Abstract
► α-Lipoic acid derived N-phenylamides, 4a-e, were synthesized. ► 4a-e were evaluated for their anti-proliferative effect on the LNCaP prostate cancer cell line. ► 4a, b, d and e showed significant reductions in cell growth at concentrations of 5-20 μM. ► Compounds validated as an excellent platform for prostate cancer nanomedical applications.
Related Topics
Physical Sciences and Engineering Chemistry Organic Chemistry
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