Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
7780965 | Carbohydrate Polymers | 2018 | 29 Pages |
Abstract
Differences in anomericity and in the branching degree of glucans lead to characteristic intermolecular association that influences their solubility in water or other solvents. A simple purification approach, based on the glucan solubility in aq. 0.1âM NaOH solution, was applied for the separation of mixed water-insoluble α-D-glucans from β-D-glucans extracted from fruiting bodies of Fomitopsis betulina, which is an underexploited medicinal mushroom. The results indicated that the β-D-glucan is constituted by (1â3)-linked β-D-Glcp units substituted at O-6 by non-reducing β-D-Glcp and (1â6)-linked β-D-Glcp units, while the α-D-glucan has a linear (1â3)-linked glucan structure. Thus, the 0.1âM NaOH treatment proved to be a simple, efficient and low-cost purification method for separation of water-insoluble glucans with different anomeric configurations and degree of branching that were interacting by intermolecular forces.
Related Topics
Physical Sciences and Engineering
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Authors
Liana Inara de Jesus, Fhernanda R. Smiderle, Lucimara M.C. Cordeiro, Rilton A. de Freitas, Leo J.L.D. Van Griensven, Marcello Iacomini,