Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
7782634 | Carbohydrate Polymers | 2018 | 39 Pages |
Abstract
Chitosan, sodium alginate and gel of Aloe vera (Aloe barbadensis Miller) were employed for the preparation of polyelectrolyte complexes at pH 4 and 6. FT-IR spectroscopy analysis showed evidence on complexes formation and incorporation of the Aloe vera gel. The ζ potential determination of the polyelectrolyte complexes revealed the presence of surface charges in the range of â20 to â24â¯mV, which results in stable systems. The dynamic moduli exhibited a high dependence on angular frequency, which is commonly found in solutions of macromolecules. The materials showed human fibroblast and lymphocyte viabilities up to 90% in agreement with null cytotoxicity. The polyelectrolyte complexes at pH 6 with Ca2+ were stable, showed high water absorption, satisfactory morphology, pore size and rigidity, characteristics that allowed significant human fibroblast migration in wound closure in vitro assays.
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Organic Chemistry
Authors
Raquel Gallardo-Rivera, MarÃa de los Ángeles Aguilar-SantamarÃa, Phaedra Silva-Bermúdez, Julieta GarcÃa-López, Alberto Tecante, Cristina Velasquillo, Angélica Román-Guerrero, César Pérez-Alonso, Humberto Vázquez-Torres, Keiko Shirai,