Wound dressings from naturally-occurring polymers: A review on homopolysaccharide-based composites

Article ID	Journal	Published Year	Pages	File Type
7783357	Carbohydrate Polymers	2018	70 Pages	PDF

Abstract

Wound dressings are designed to support the wound bed and protect it from the factors that may delay or impede its healing such as contaminations and moisture-loss, thereby facilitating and accelerating the healing process. The materials used to prepare wound dressings include natural and synthetic polymers, as well as their combinations, in the forms of films, sponges and hydrogels. Polysaccharides are naturally-occurring polymers that have been extensively used as wound dressing materials. Homopolysaccharides are a class of polysaccharides consist of only one type of monosaccharide. The current review intends to overview the studies in which wound dressings from naturally-occurring polymers, based on homopolysaccharides, were prepared and evaluated. Homopolysaccharides such as cellulose, chitosan, chitin, pullulan, starch and Î²-glucan were considered.

Keywords

WST-1 SRB ECM B. subtilis HUVECS DAPI MTS CFC CuO NaBH4 Three-dimensional HEK293 P. aeruginosa HDFs AgNO3 Citrobacter freundii 2-(4-iodophenyl)-3-(4-nitrophenyl)-5-(2,4-disulfophenyl)-2H-tetrazolium, monosodium salt 2-(2-methoxy-4-nitrophenyl)-3-(4-nitrophenyl)-5-(2,4-disulfophenyl)-2H-tetrazolium, monosodium salt Bacillus subtilis WST-8 L02 cells WVTR Komagataeibacter xylinus Inhibition zone diameter PBS C. albicans E. coli K. pneumonia 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide 4',6-diamidino-2-phenylindole DNA MTT NPs RAW 264.7 cells ROS S. Epidermidis Adenosine Triphosphate ATP Staphylococcus aureus MRSA methicillin-resistant Staphylococcus aureus S. aureus Staphylococcus epidermidis deoxyribonucleic acid RNA ribonucleic acid Escherichia coli Wound Healing Zinc oxide ZnO Copper oxide Sodium borohydride TiO2 Titanium dioxide L929 cells MDCK cells Vero cells Human umbilical vein endothelial cells african green monkey kidney cells human embryonic kidney cells Madin-Darby canine kidney cells Pseudomonas aeruginosa Silver sulfadiazine sulforhodamine B Vascular endothelial growth factor Vascular Endothelial Growth Factor (VEGF)Human dermal fibroblasts lactate dehydrogenase LDH Extracellular matrix Phosphate-buffered saline SEM mouse embryonic fibroblasts scanning electron microscope Nanoparticles Water vapor transmission rate silver nitrate Wound dressing Klebsiella pneumonia Polysaccharide optical density Candida albicans human skin keratinocytes Reactive oxygen species