Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
7784677 | Carbohydrate Polymers | 2018 | 9 Pages |
Abstract
From transport studies on Caco-2 cells, resulted that INVITESA nanomicelles cross the cellular monolayer but are actively re-transported in the secretory (basolateral-apical) direction when loaded in apical side. It suggests that the entrapped drug could not be absorbed before the release from the micelles, enabling so a local release of the active.
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Authors
Delia Mandracchia, Adriana Trapani, Sara Perteghella, Milena Sorrenti, Laura Catenacci, Maria Luisa Torre, Giuseppe Trapani, Giuseppe Tripodo,