Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
7784748 | Carbohydrate Polymers | 2018 | 9 Pages |
Abstract
A nano-composite from biologically obtained chitin nanofillers homogenously dispersed in a poly(ε-caprolactone) matrix was successfully achieved by an ultrasonication-assisted non-toxic and non-aqueous methodology. For this purpose, biological chitin was obtained from lactic acid fermentation of shrimp wastes and converted into chitin whiskers by acidic hydrolysis in a novel process at low temperature (4 °C) that enhanced the distribution and yield. Additionally, the polyester matrix was enzymatically produced in a non-toxic compressed fluid (1,1,1,2-tetrafluoroethane at 25 bar and 65 °C) medium. The homogeneous distribution of the nanofiller in the matrix was corroborated by confocal and atomic force microscopies. Films of the nanocomposite were physicochemically characterized to assess its adequate properties. Additionally, the qualitative viability of human fibroblasts and osteoblasts cells was studied on the produced nanocomposite films showing good biocompatibility.
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Andres EspadÃn, Lenin Tamay De Dios, Erika Ruvalcaba, Josefina Valadez-GarcÃa, Cristina Velasquillo, Ismael Bustos-Jaimes, Humberto Vázquez-Torres, Miquel Gimeno, Keiko Shirai,