Water soluble polysaccharides extracted from Pterocladia capillacea and Dictyopteris membranacea and their biological activities

Cold and hot water extracts (CWE, HWE) of both the red alga Pterocladia capillacea (P. capillacea) and the brown alga Dictyopteris membranacea (D. membranacea) were studied for their polysaccharide contents. In both (CWE) and (HWE) extracts. Relatively higher yields were obtained in case of P. capillacea pillacea (2.87 and 6.46%, respectively). The polysaccharide contents of the CWE hydrolyzate of both studied algae analyzed by HPLC were found to be enriched with glucuronic acid, arabinose and glucose, whereas, HWE hydrolyzate were found to be rich in glucuronic acid and fructose. The polysaccharide contents of the CWE and HWE extracts of (D. membranacea) showed appreciable antimicrobial activity in addition to a moderate antitumor activity against HELA (Cervix carcinoma cell line) at IC50 = 9.83 μg/dl, respectively. Whereas the polysaccharide contents of the CWE and HWE extracts of (P. capillacea) exhibited a promising anticoagulant activity.