Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
7791793 | Carbohydrate Polymers | 2014 | 7 Pages |
Abstract
The main aim of this study was to investigate the effect of different coating materials (i.e. Na-alginate and chitosan) on the viability and release behavior of Bifidobacterium pseudocatenulatum G4 in the simulated gastric fluid (SGF) and simulated intestinal fluid (SIF). This study reports the viability of encapsulated B. pseudocatenulatum G4 coated using different alginate (2-4Â g/100Â mL) and chitosan (0.2-0.8Â g/100Â mL) concentrations. The results indicated that the highest concentration of alginate (4.4142Â g/100Â mL) along with 0.5578Â g/100Â mL chitosan resulted in the highest viability of B. pseudocatenulatum G4. The release behavior of the encapsulated probiotics in SGF (pH 1.5) in 2Â h followed by 4Â h in SIF (pH 7.4) was also assessed. The resistance rate of alginate-chitosan capsule in SGF was higher than SIF. The alginate-chitosan encapsulated cells had also more resistance than alginate capsules. The current study revealed that alginate encapsulated B. Pseudocatenulatum G4 exhibited longer survival than its free cells (control).
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Authors
Nikoo Kamalian, Hamed Mirhosseini, Shuhaimi Mustafa, Mohd Yazid Abd Manap,