Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
7791910 | Carbohydrate Polymers | 2014 | 13 Pages |
Abstract
The formation of host-guest inclusion complex of 2,4-dinitroaniline (2,4-DNA) with nano-hydrophobic cavity of β-cyclodextrin (β-CD) in solution phase were studied by UV-visible spectrophotometer and electrochemical method (Cyclic Voltammetry, CV). The prototropic behaviors of 2,4-DNA with and without β-CD was studied by spectrophotometrically. The binding constant of the inclusion complex at 303 K was calculated using Benesi-Hildebrand plot and thermodynamic parameter (ÎG) were also calculated. The inclusion complex formation between β-CD and 2,4-DNA was confirmed by 1H NMR, 2D ROESY NMR, FT-IR, XRD and SEM analysis. The 2,4-DNA:β-CD inclusion complex was obtained by molecular docking studies and it was good correlation with the results obtained through experimental methods.
Keywords
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Thambusamy Stalin, Krishnan Srinivasan, Krishnamoorthy Sivakumar, S. Radhakrishnan,