| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 7792199 | Carbohydrate Polymers | 2014 | 7 Pages |
Abstract
Poly(vinyl alcohol) (PVA) has been grafted with glycolic acid (GL), a biodegradable hydroxyl acid to yield modified poly(vinyl alcohol) (PVAGL). The formation of hydrogels at pHÂ =Â 6.8 and physiological temperature through blending chitosan (CS) and PVAGL at different concentrations has been investigated. FTIR, DOSY NMR and oscillatory rheology measurements have been carried out on CS/PVAGL hydrogels and the results have been compared to those obtained for CS/PVA hydrogels prepared under the same conditions. The experimental results point to an increase in the number of interactions between chitosan and PVAGL in polymer hydrogels prepared with modified PVA. The resulting materials with enhanced elastic properties and thixotropic behavior are potential candidates to be employed as injectable materials for biomedical applications.
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Authors
A. Lejardi, R. Hernández, M. Criado, Jose I. Santos, A. Etxeberria, J.R. Sarasua, C. Mijangos,