The Staudinger/aza-Wittig/Grignard reaction as key step for the concise synthesis of 1-C-Alkyl-iminoalditol glycomimetics

- The Staudinger/aza-Wittig Grignard reaction cascade is a concise synthetic method for the synthesis of biologically active 1-C-alkyl iminoalditol glycomimetics.
- A concise synthetic approach to biologically active 1-C-alkyl iminoalditol glycomimetics: The Staudinger/aza-Wittig Grignard reaction cascade.
- The stereoselective control of C-1 alkyl substitution can be controlled by the choice of protecting groups at the sugar substrate as well as the nature of the nucleophilic Grignard reagent in the Staudinger/aza-Wittig Grignard reaction cascade.
- Compounds exhibit selective b-glucosidase inhibition.