Synthesis of C-5a-substituted derivatives of 4-epi-isofagomine: notable Î²-galactosidase inhibitors and activity promotors of GM1-gangliosidosis related human lysosomal Î²-galactosidase mutant R201C

Article ID	Journal	Published Year	Pages	File Type
7793972	Carbohydrate Research	2016	10 Pages	PDF

Keywords

Iminoalditol GM1-gangliosidosis Pharmacological chaperone Galactosidase inhibitor

Related Topics

Physical Sciences and Engineering Chemistry Organic Chemistry

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Synthesis of C-5a-substituted derivatives of 4-epi-isofagomine: notable Î²-galactosidase inhibitors and activity promotors of GM1-gangliosidosis related human lysosomal Î²-galactosidase mutant R201C

Authors

Martin Thonhofer, Patrick Weber, Andres Gonzalez Santana, Christina Tysoe, Roland Fischer, Bettina M. Pabst, Eduard Paschke, Michael Schalli, Arnold E. Stütz, Marion Tschernutter, Werner Windischhofer, Stephen G. Withers,