| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 7794000 | Carbohydrate Research | 2016 | 8 Pages |
Abstract
- N-1,3-dihydroxypropylaminocyclitols were synthesized from natural (+)-proto-quercitol through reductive amination.
- The target compounds were potent competitive inhibitors against rat intestinal maltase and sucrase with submicromolar Ki values.
- Docking study indicated that the cyclohexane rings of voglibose and the synthesized compounds are tilted relative to that of miglitol.
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Authors
Wisuttaya Worawalai, Pornthep Sompornpisut, Sumrit Wacharasindhu, Preecha Phuwapraisirisan,