| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 7794463 | Carbohydrate Research | 2014 | 49 Pages |
Abstract
- Gemcitabine is a 2â²,2â²-difluorinated nucleoside.
- The 2-deoxy-2,2-difluorinated ribose has been synthesised by a variety of approaches.
- The sugar fluorination required modified nucleobase introduction.
- Extensive efforts to achieve diastereomerically pure intermediates are described.
Keywords
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Kylie Brown, Michael Dixey, Alex Weymouth-Wilson, Bruno Linclau,