Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
7794595 | Carbohydrate Research | 2014 | 8 Pages |
Abstract
- A stereoselective synthesis of 2â²-C-cyano pyranonucleosides was accomplished.
- 2â²-Spiro nucleosides were synthesized via their key intermediate cyanohydrins.
- Structural elucidation of the synthesized compounds by NMR studies.
- Several 5-fluorouracil derivatives showed a pronounced cytostatic activity.
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Christos Kiritsis, Stella Manta, Athina Dimopoulou, Vanessa Parmenopoulou, Petros Gkizis, Jan Balzarini, Dimitri Komiotis,