| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 7795168 | Carbohydrate Research | 2012 | 11 Pages |
Abstract
⺠First attempt at including donor, acceptor, promoter, and solvent in glycoside formation modeling. ⺠Long range (2.725 Ǻ) interactions of acceptor oxygens with donor C-1 during ionization identified. ⺠Promoter in TS and is the most strongly solvated molecule. ⺠SSIP-like Transition States identified for α- or β- attack on β- or α-triflates. ⺠Orientation of the nucleophile identified as key determinant of stereospecificity.
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Authors
Dennis M. Whitfield,