Article ID Journal Published Year Pages File Type
7796099 European Journal of Medicinal Chemistry 2018 20 Pages PDF
Abstract
With a rational design strategy, a triphenylphosphonium cation moiety and a nitro group were incorporated into 1a, affording 1f with improved target inhibition and selectivity.231
Keywords
Related Topics
Physical Sciences and Engineering Chemistry Organic Chemistry
Preview
Rational design of mitochondria-targeted pyruvate dehydrogenase kinase 1 inhibitors with improved selectivity and antiproliferative activity
Authors
, , , , , ,