Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
7796126 | European Journal of Medicinal Chemistry | 2018 | 37 Pages |
Abstract
A novel monofunctional platinum-based RNA polymerase I selective inhibitor, P1-B1, displays significant nucleolar accumulation, selectively inhibits Pol I transcription, and induces p53 activation as well as nucleolar stress.287
Keywords
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Zhen-Lei Zhang, Chun-Lai Zhao, Qian Chen, Kai Xu, Xin Qiao, Jing-Yuan Xu,