Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
7796433 | European Journal of Medicinal Chemistry | 2018 | 18 Pages |
Abstract
New benzothiazinones bearing a piperidine moiety were designed and synthesized as antitubercular agents based on the structure feature of IMB-ZR-1 discovered in our lab. Compound 2i were found to display potent anti-TB activity (MICâ¯<â¯0.016â¯Î¼g/mL) against drug-sensitive/resistant MTB strains.100
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Kai Lv, Zeyu Tao, Qian Liu, Lu Yang, Bin Wang, Shuo Wu, Apeng Wang, Menghao Huang, Mingliang Liu, Yu Lu,