| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 7796470 | European Journal of Medicinal Chemistry | 2018 | 36 Pages |
Abstract
Novel azacalix[2]arene[2]pyrimidines were designed and synthesized. Compound 4j exhibited strong inhibitory activity against MCF7 cells, and its mechanisms were involved in inducing apoptosis via up-regulation of caspase-3 and caspase-9â¯cell and cycle arrest at the S phase.182
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
![Synthesis and anticancer activity evaluation of novel azacalix[2]arene[2]pyrimidines](/preview/png/7796470.png "First Page Preview: Synthesis and anticancer activity evaluation of novel azacalix[2]arene[2]pyrimidines")
Authors
Yesu Addepalli, Xiaohong Yang, Minghui Zhou, D. Prabhakar Reddy, Shao-Lin Zhang, Zhen Wang, Yun He,