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Design and synthesis of furyl/thineyl pyrroloquinolones based on natural alkaloid perlolyrine, lead to the discovery of potent and selective PDE5 inhibitors

Article ID Journal Published Year Pages File Type
7796482 European Journal of Medicinal Chemistry 2018 25 Pages PDF
Keywords
BioavailabilityPDE5 Inhibitors
Related Topics
Physical Sciences and Engineering Chemistry Organic Chemistry
Preview
Design and synthesis of furyl/thineyl pyrroloquinolones based on natural alkaloid perlolyrine, lead to the discovery of potent and selective PDE5 inhibitors
Authors
Hongbo Zheng, Lin Li, Bin Sun, Yun Gao, Wei Song, Xiaoyu Zhao, Yanhui Gao, Zhiyu Xie, Nianzhao Zhang, Jianbo Ji, Huiqing Yuan, Hongxiang Lou,
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Journal
European Journal of Medicinal Chemistry
Journal: European Journal of Medicinal Chemistry
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