| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 7796500 | European Journal of Medicinal Chemistry | 2018 | 34 Pages |
Abstract
A series of novel 6-chloro-2-(propylthio)-8,9-dihydro-7H-purines containing a carboxamide moiety were synthesized and evaluated for their antiproliferative activity. SAR studies showed that compound 8 could inhibit the colony formation and migration as well as induce apoptosis of A549â¯cells.381
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Tao-Qian Zhao, Yuan-Di Zhao, Xin-Yang Liu, Bo Wang, Zhong-Hua Li, Zhang-Xu He, Xin-Hui Zhang, Jian-Jia Liang, Li-Ying Ma, Hong-Min Liu,