| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 7796552 | European Journal of Medicinal Chemistry | 2018 | 17 Pages |
Abstract
Three iridium (III) complexes [Ir(N-C)2 (ipbc)](PF6) (N-Câ¯=â¯ppy, Ir-1; bzq, Ir-2; piq, Ir-3) were synthesized and characterized. The anticancer activity of the complexes was investigated by apoptosis, comet assay, ROS, mitochondrial membrane potential, autophagy, intracellular Ca2+ levels, release of cytochrome c, tubules and western blot analysis.308
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Authors
Wen-Yao Zhang, Qian-Yan Yi, Yang-Jie Wang, Fan Du, Miao He, Bing Tang, Dan Wan, Yun-Jun Liu, Hong-Liang Huang,