New insights in the structure-activity relationships of 2-phenylamino-substituted benzothiopyrano[4,3-d]pyrimidines as kinase inhibitors

Article ID	Journal	Published Year	Pages	File Type
7796560	European Journal of Medicinal Chemistry	2018	35 Pages	PDF

Keywords

TKR KDR kinase A-431 KDR VEGFR HUVEC SAR Human Structure-activity relationships Human umbilical vein endothelial cell Vascular endothelial growth factor Vascular Endothelial Growth Factor (VEGF)Antiproliferative activity Kinase inhibitors Hela Tyrosine kinase receptor vascular endothelial growth factor receptor

Related Topics

Physical Sciences and Engineering Chemistry Organic Chemistry

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New insights in the structure-activity relationships of 2-phenylamino-substituted benzothiopyrano[4,3-d]pyrimidines as kinase inhibitors

Authors

Silvia Salerno, AÃda Nelly GarcÃa-Argáez, Elisabetta Barresi, Sabrina Taliani, Francesca Simorini, Concettina La Motta, Giorgio Amendola, Stefano Tomassi, Sandro Cosconati, Ettore Novellino, Federico Da Settimo, Anna Maria Marini, Lisa Dalla Via,