| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 7796578 | European Journal of Medicinal Chemistry | 2018 | 42 Pages |
Abstract
Compound 11 selectively inhibited STAT3 activation to exert antitumor activity.199
Keywords
TMStetramethylsilaneSH2GAPDHERKDMSOMTTROSSTATSelectivityApoptosisRoom temperatureDimethyl sulfoxideSulfonamideStructure-based drug designAntitumor activitySignal transducer and activator of transcriptionPropidium iodideextracellular regulated kinaseglyceraldehyde-3-phosphatedehydrogenaseReactive oxygen species
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Jianpeng Guo, Wenying Yu, Guiping Cai, Wenda Zhang, Shanshan Li, Jiawen Zhu, Dongmei Song, Lingyi Kong,