| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 7796788 | European Journal of Medicinal Chemistry | 2018 | 41 Pages |
Abstract
Novel tricyclic scaffolds were discovered as selective BuChE inhibitors. Compounds 3f and 3o with dihalogen and a 6-ethyl substituent exhibited the most potent activity. Compound 3o showed remarkable neuroprotective activity.270
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
![Tricyclic pyrazolo[1,5-d][1,4]benzoxazepin-5(6H)-one scaffold derivatives: Synthesis and biological evaluation as selective BuChE inhibitors](/preview/png/7796788.png "First Page Preview: Tricyclic pyrazolo[1,5-d][1,4]benzoxazepin-5(6H)-one scaffold derivatives: Synthesis and biological evaluation as selective BuChE inhibitors")
Authors
Shi-Chao Chen, Guo-Liang Qiu, Bo Li, Jing-Bo Shi, Xin-Hua Liu, Wen-Jian Tang,