| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 7797161 | European Journal of Medicinal Chemistry | 2018 | 43 Pages |
Keywords
IC90DTUsNifurtimoxTCTCMCCC50nIFCyPRPMIIC50ADMET2′,7′-dichlorodihydrofluorescein diacetateDMSOH2DCFDAROSAdenosine TriphosphateATPEDTAethylenediamine tetraacetic acidBenznidazoleTrypanosoma cruziabsorption, distribution, metabolism, excretion and toxicityDimethyl sulfoxideCardiac muscle cellsCytochrome P450selectivity indexChagas diseaseChemotherapyTrypanocidal activityRoswell Park Memorial InstituteNaphthoquinonesReactive oxygen species
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
![Efficacy of 2-hydroxy-3-phenylsulfanylmethyl-[1,4]-naphthoquinone derivatives against different Trypanosoma cruzi discrete type units: Identification of a promising hit compound](/preview/png/7797161.png "First Page Preview: Efficacy of 2-hydroxy-3-phenylsulfanylmethyl-[1,4]-naphthoquinone derivatives against different Trypanosoma cruzi discrete type units: Identification of a promising hit compound")
Authors
L.S. Lara, C.S. Moreira, C.M. Calvet, G.C. Lechuga, R.S. Souza, S.C. Bourguignon, V.F. Ferreira, D. Rocha, M.C.S. Pereira,