Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
7797209 | European Journal of Medicinal Chemistry | 2018 | 30 Pages |
Keywords
HOBtDCMTESNeuromedin UTICACNIC50HEKDAPdiisopropyl carbodiimideSPATFAEC50inositol triphosphateHBSSDMTIP3GPCRFMOCDMFNeuromedin U (NMU)SARDMEMTriethylsilaneNMU9-FluorenylmethyloxycarbonylSPPSTBTUHEPESDICEmaxOIC1-hydroxybenzotriazole1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid4-(2-hydroxyethyl)-1-piperazineethanesulfonic acidAUCDMSODulbecco's modified Eagle MediumHanks balanced salt solutionN,N-diisopropylethylaminemaximal effectAcetonitrileTrifluoroacetic acidFormic acidScintillation proximity assayCNSRoom temperaturedimethylformamideDichloromethaneDimethyl sulfoxideStructure activity relationshipsubcutaneousSolid phase peptide synthesiscentral nervous systemMass spectrometryarea under the curveDIPEAhalf maximal inhibitory concentrationhalf maximal effective concentrationPlasma stabilitypolyethylene glycolPEGhigh performance liquid chromatographyHPLChuman embryonic kidneyG protein-coupled receptor
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
An De Prins, Charlotte Martin, Yannick Van Wanseele, Louise Julie Skov, Csaba Tömböly, Dirk Tourwé, Vicky Caveliers, Ann Van Eeckhaut, Birgitte Holst, Mette Marie Rosenkilde, Ilse Smolders, Steven Ballet,