| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 7797359 | European Journal of Medicinal Chemistry | 2018 | 34 Pages |
Abstract
A series of pyrrolo[2,3-b]pyridine derivatives bearing 1,8-naphthyridin-2-one moiety (23-54) were designed, synthesized and evaluated for their activity against four cancer cell lines and six tyrosine kinases. The most promising compound 32 showed excellent activity in vitro.185
Related Topics
Physical Sciences and Engineering
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Organic Chemistry
![Synthesis and antiproliferative activity of pyrrolo[2,3-b]pyridine derivatives bearing the 1,8-naphthyridin-2-one moiety](/preview/png/7797359.png "First Page Preview: Synthesis and antiproliferative activity of pyrrolo[2,3-b]pyridine derivatives bearing the 1,8-naphthyridin-2-one moiety")
Authors
Qidong Tang, Yongli Duan, Linxiao Wang, Min Wang, Yiqiang Ouyang, Caolin Wang, Han Mei, Sheng Tang, Yinhua Xiong, Pengwu Zheng, Ping Gong, Wufu Zhu,