| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 7797450 | European Journal of Medicinal Chemistry | 2018 | 49 Pages |
Abstract
A series of O2-(2,4-dinitrophenyl) diazeniumdiolates derivatives were designed, synthesized and antiproliferative activities evaluated as novel nitric oxide (NO)-releasing prodrugs that could be activated by glutathione S-transferases Ï (GSTÏ). Compound 36 showed remarkably multidrug resistance reversal activity which reversed multidrug resistance of adriamycin (ADR) in MCF-7/ADR cells.237
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Authors
Qixing Li, Pian Zou, Jianbo Sun, Li Chen,